Hepatitis E Pathogenesis

Hepatitis E Pathogenesis

Although most hepatitis E virus (HEV) infections are asymptomatic, some can be severe, causing fulminant hepatitis and extra-hepatic manifestations, including neurological and kidney injuries. Chronic HEV infections may also occur in immunocompromised patients. This review describes how our understanding of the pathogenesis of HEV infection has progressed in recent years.

Hepatitis E Virus Infection: Pathogenesis and Therapy

Structure and Function of the Hepatitis E Virus Capsid Related to Hepatitis E Pathogenesis

There are five different types of viral hepatitis (A, B, C, D, and E) in the world, each of which caused by a different virus. Although they all cause the disease in human, the five viruses are unrelated and are from different virus families with totally different genome structures and distinct replication mechanisms (Fauquet et al., 2005; Hochman & Balistreri, 1999; Kumar et al., 2010). Hepati...

Hepatitis E

Hepatitis E virus (HEV) was discovered during the Soviet occupation of Afghanistan in the 1980s, after an outbreak of unexplained hepatitis at a military camp. A pooled faecal extract from affected soldiers was ingested by a member of the research team. He became sick, and the new virus (named HEV), was detected in his stool by electron microscopy. Subsequently, endemic HEV has been identified ...

Hepatitis E.

From the Liver Disease Research Branch, Division of Digestive Diseases and Nutrition, National Institute of Diabetes and Digestive and Kidney Diseases (J.H.H.), and the Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases (R.H.P.), National Institutes of Health, Bethesda; and the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Bal...